In screening operations across mining, metallurgy, and coal industries, polyurethane screens are widely valued for their wear resistance, impact strength, and high screening efficiency. However, frequent blinding issues significantly reduce productivity and increase maintenance costs. Based on industry research, this article systematically analyzes the core causes of blocking, ranked by impact, including material characteristics (e.g., particle size mismatch, high mud content, moisture), improper screen design (low open area, unsuitable hole shape), incorrect equipment parameters (insufficient vibration frequency, inappropriate angle), and operational errors. It also offers practical emergency solutions that can be quickly implemented on-site, such as physical cleaning, parameter adjustments, and feed control, to help enterprises restore screening efficiency and reduce downtime. This guide provides a comprehensive resource for industry professionals seeking effective blinding solutions.