Polyurethane dewatering screen panel are widely used in coal preparation plants for coal dewatering and classification, but their performance is highly dependent on proper usage and maintenance. Based on actual operating conditions, this article systematically outlines key considerations across five core stages: selection, installation, operation, maintenance, and storage. The selection phase emphasizes precise matching based on coal quality characteristics and screen parameters; installation focuses on standardized procedures and inspections; operation provides guidance on real-time monitoring and load control; maintenance offers periodic upkeep and troubleshooting solutions; and storage ensures material protection against aging. Through comprehensive lifecycle management, this approach significantly extends screen plate lifespan, enhances screening efficiency, and reduces operational costs. This guide serves coal preparation plant operators, equipment managers, and technical engineers to achieve efficient and safe screening operations.